Hexarelin 2mg

Hexarelin is a synthetic hexapeptide growth hormone secretagogue (His-D-2-MeTrp-Ala-Trp-D-Phe-Lys-NH₂) that binds to the GHS-R1a receptor. It stimulates the signaling cascade of the growth hormone axis via Gq-protein pathways, and it has been shown to influence pituitary–hypothalamic regulation as well as cardiac peptide physiology in experimental models. Hexarelin is widely used to investigate the peptide receptor interaction and the modulation of endocrine signals.

Hexarelin (also known as Examorelin) is a synthetic analogue of ghrelin and closely related to GHRP-6. Hexarelin and GHRP-6 differ only marginally, generally described as the addition of methyl groups to the GHRP-6 backbone. As with many ghrelin analogs, Hexarelin has been described in research discussions as orally and sublingually active and is considered highly selective.

Hexarelin has been intensively studied in preclinical and translational research, particularly with regard to signaling pathways involved in the survival of cardiomyocytes, especially in situations that involve ischemia (reduced blood flow) and nutrient deprivation.