MOTS-c 10mg

MOTS-c is a research peptide derived from mitochondria, consisting of 16 amino acids (Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg). It is encoded in the mitochondrial 12S rRNA gene and acts as a metabolic regulator that influences AMPK activation, insulin sensitivity, and mitochondrial homeostasis in preclinical models. MOTS-c is used in studies that investigate cellular adaptation to stress, energy signals, and age-related metabolic regulation.

MOTS-c is a short peptide encoded in the mitochondrial genome, and a member of the larger group of mitochondria-derived peptides (MDPs). MDPs were recently identified as bioactive hormones that play an important role in mitochondrial signaling and energy regulation. Originally it was thought that they were only associated with the mitochondria, but new research has shown that many MDPs are active in the cell nucleus and that some even reach the bloodstream to exert systemic effects. MOTS-c is a newly identified MDP, to which so far an important role has been attributed in metabolism, weight regulation, training capacity, longevity, and even processes linked to disease states such as osteoporosis. MOTS-c has been found both in the cell nucleus of cells and in the general circulation, making it a true natural hormone. The peptide has been the focus of intensive research in the last five years due to its therapeutic potential.