Tripeptide-29 is a research peptide composed of Gly-Pro-Hyp, a collagen-derived tripeptide fragment, whose role in the synthesis of the extracellular matrix and the regulation of fibroblasts is being investigated. Experimental studies show that Tripeptide-29 modulates the gene expression of collagen type I, promotes ECM remodeling, and stabilizes the protein architecture of the dermis in in vitro models. It serves as a model compound for research on peptide-mediated tissue repair, structural protein turnover, and cellular communication within connective tissue systems.