CJC-1295 (non-DAC), also known as Mod GRF (1–29), is a tetra-substituted analog of the growth hormone-releasing hormone (GHRH 1–29) developed to improve metabolic stability and receptor affinity without DAC conjugation.
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Ask AssistantCJC-1295 (non-DAC), also known as Mod GRF (1–29), is a tetra-substituted analog of the growth hormone-releasing hormone (GHRH 1–29) developed to improve metabolic stability and receptor affinity without DAC conjugation. It acts on the GHRH receptor to stimulate adenylyl cyclase and the cAMP signaling, which leads to pulsatile growth hormone release in controlled experimental settings. Mod GRF (1–29) is widely used in studies of somatotropic regulation, peptide kinetics, and endocrine signaling.
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