Sermorelin
Sermorelin is a synthetic investigational peptide that comprises the first 29 amino acids of growth hormone-releasing hormone (GHRH 1–44) and represents its biologically active domain.
Research dossier
Sermorelin
Research DossierSermorelin
SequenceTyr-DL-Ala-DL-Asp-DL-Ala-DL-xiIle-DL-Phe-DL-xiThr-DL-Asn-DL-Ser-DL-Tyr-DL-Arg-DL-Lys-DL-Val-DL-Leu-Gly-DL-Gln-DL-Leu-DL-Ser-DL-Ala-DL-Arg-DL-Lys-DL-Leu-DL-Leu-DL-Gln-DL-Asp-DL-xiIle-DL-Met-DL-Ser-DL-Arg
FormulaC149H246N44O42S
Mol. Weight3357.933 g/mol
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$35USD / dossier
Sequence
Tyr-DL-Ala-DL-Asp-DL-Ala-DL-xiIle-DL-Phe-DL-xiThr-DL-Asn-DL-Ser-DL-Tyr-DL-Arg-DL-Lys-DL-Val-DL-Leu-Gly-DL-Gln-DL-Leu-DL-Ser-DL-Ala-DL-Arg-DL-Lys-DL-Leu-DL-Leu-DL-Gln-DL-Asp-DL-xiIle-DL-Met-DL-Ser-DL-Arg
Molecular Formula
C149H246N44O42S
Molecular Weight
3357.933 g/mol
PubChem CID
16129620
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Sermorelin is a synthetic investigational peptide that comprises the first 29 amino acids of growth hormone-releasing hormone (GHRH 1–44) and represents its biologically active domain. It binds to the GHRH receptor on pituitary somatotrophs, activates adenylyl cyclase and cAMP-mediated signal transduction to stimulate GH synthesis and release in preclinical models. Sermorelin is used in studies that investigate hypothalamic–pituitary regulation, endocrine feedback, and somatotropic peptide signaling.
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