Ipamorelin 5mg

Ipamorelin is a pentapeptide growth hormone secretagogue (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) that selectively acts on the ghrelin receptor (GHS-R1a). It stimulates the release of GH via cAMP- and calcium-dependent signaling pathways, without affecting prolactin or cortisol secretion. Ipamorelin serves as a research instrument for studying G-protein signaling, endocrine feedback mechanisms, and hypothalamic regulation.

Ipamorelin is a short peptide sequence that can bind to the ghrelin/growth hormone secretagogue receptor. It is among the most selectively known growth hormone secretagogues, and laboratory studies have shown that it has no effect on ACTH, prolactin, follicle-stimulating hormone, luteinizing hormone, thyroid-stimulating hormone, or cortisol release [1]. Given its high degree of specificity, Ipamorelin is of interest in research both as a standalone therapeutic substance and as a model peptide to understand how selectivity in receptor binding is achieved.